Frequently Asked QuestionsWhy does vanilla perfume smell different on everyone? “Body temperature can also play a role, as warmer skin can intensify certain base notes, vanilla and amber being two examples,” Jelk explains. How do you layer vanilla perfume with other scents? We review ingredients, scrutinize brand claims, and, when necessary, examine peer-reviewed scientific and medical studies. For our review of the best vanilla perfumes, we enlisted the help of multiple editors, writers, and contributors to review the products.