The kissing bug disease has nothing to do with you or anyone else showing affection - mostlySteven Van Elk via Unsplash Steven Van Elk via Unsplash loading... Infographic, CDC Infographic, CDC loading...How can you prevent being affected by the kissing bug disease? They say "staying in well-built places" will help you avoid being infected by bugs carrying the kissing disease. What are symptoms of the kissing bug disease? The bottom line is you don't want any part of the kissing bug disease and now Missouri is among the states that needs to be the most careful.