Tuscaloosa is one of the most expensive places to live in the United States. Would you choose Tuscaloosa over all of the resort towns in California, Florida, or Savannah, Georgia? According to a new study released this week, our home in West Alabama, Tuscaloosa, is one of the most expensive cities in America for rent. Yet, Tuscaloosa costs more to rent a place than those resort and vacation cities. Tuscaloosa is one of the most expensive cities in AMERICA to rent a house or apartment.