San Fran setback San Francisco 49ers handed devastating injury blow as key defensive superstar is ruled out for season with torn ACLTHE San Francisco 49ers have been handed a devastating injury blow to one of their defensive superstar. The star in question has been ruled out for the season with a torn ACL. 2 Nick Bosa has been ruled out for the rest of the season with another torn ACL Credit: AP2 Bosa went down in the first half vs the Cardinals with his third ACL injury of his career Credit: APLineman Nick Bosa will miss the rest of the 2025 NFL season after his third ACL injury. He won the NFL Defensive Rookie of the Year award in his first season and won the Defensive Player of the Year award in 2022. How to watch NFL games in 2025 THE 2025 NFL season is fast approaching and you can get some excellent deals to watch all the action.