New Delhi, October 3 (IANS): Glioblastomas -- the deadliest form of brain cancer -- affect much more than just the brain, scientists have found. A team from the Montefiore Einstein Comprehensive Cancer Center (MECCC) and Albert Einstein College of Medicine has found the first evidence to show that glioblastoma can erode the skull, alter the makeup of skull marrow, and interfere with the body's immune response. As is true for many other bones, the skull contains marrow in which immune cells and other blood cells form. The researchers hypothesised that these channels might allow the glioblastoma to transmit signals to the skull marrow that could profoundly change its immune landscape. Further, the team found that glioblastoma activated several genes in the skull marrow that boosted production of inflammatory immune cells, but in femur marrow, the cancer suppressed genes needed to produce several types of immune cells.