The new flight route will connect London Heathrow to St. Louis, a prominent city in Missouri at the heart of the Midwest. ‌Famous for its iconic Gateway Arch and vibrant neighbourhoods, the UK airline believes St. Louis has something for every visitor. British Airways claims to serve more American cities than any other UK airline, with St. Louis set to become its 27th. The launch will also make British Airways the only UK airline operating direct flights to St. Louis. ‌The St. Louis launch coincides with the 100th anniversary of Route 66, the famous highway that begins in Chicago, passes through St. Louis, and continues to Los Angeles.