Then the undermanned 49ers outplayed a heavily favored Los Angeles Rams team on Thursday night. pic.twitter.com/5kT7gBYVt2 — San Francisco 49ers (@49ers) October 3, 2025 Expand TweetNFL Network insider Ian Rapoport became in awe of the final defensive stop, saying “what a stand” on that critical sequence to win the game. What a game by a very depleted #49ers team. 49ers dealt with injury pileup before & during Rams gameAgain, the 49ers were a walking medical case in this TNF matchup. Kendrick Bourne reels in his NINTH reception of the night 👀 pic.twitter.com/WlKnjGxf65 — ClutchPoints (@ClutchPoints) October 3, 2025Christian McCaffrey combined for 139 total yards and scored one receiving touchdown.