New England Patriots defensive tackle Milton Williams (97) prepares to run onto the field before an NFL football game against the Miami Dolphins, Saturday, Sept. 14, 2025, in Miami Gardens, Fla. (AP Photo/Doug Murray) APFOXBOROUGH – Will the Patriots be missing a key piece this weekend? The game-wrecking defensive tackle popped up on the injury report this week when he was limited in Wednesday’s session with an ankle injury. On Wednesday, before practice, Williams said he was looking forward to the Patriots’ upcoming matchup in Buffalo. It’s going to be a fun environment to play in.”If Williams can’t play on Sunday in Buffalo, it’ll create a massive void in the Patriots defensive line. This game will be big for the Patriots defensive line as they try to contain Bills quarterback Josh Allen and running back James Cook.