Shafaqna English- Scientists have directly observed a toxic protein drilling dynamic, pore-like holes into brain cells—a breakthrough that could reshape understanding of Parkinson’s disease. The study, published in ACS Nano, reveals that these pores open and close like “molecular revolving doors,” potentially allowing ions and other molecules to leak into cells and disrupt their function. This mechanism may explain the slow progression of Parkinson’s, as cells struggle to compensate for repeated damage. The team used artificial vesicles mimicking brain cell membranes to observe the entire pore formation process in slow motion. While conducted in simplified models, the study offers a powerful new method for screening drug candidates and understanding early disease mechanisms.