The Bills are the class of the AFC as the conference’s only undefeated team, however. The Patriots are 7.5-point underdogs but can still prove something on the road, in primetime against a very good opponent. The Patriots also could have beaten the Steelers in Week 3 if they hadn’t turned the ball over five times. The Bills have only turned the ball over once this season, while the Patriots have six giveaways. So, ball security will be key if the Patriots hope to leave Buffalo with an upset.