I've had a bone to pick with Louisville highways for a long time. Louisville Road WorkI'm not kidding. We were in Louisville a lot when I was a kid in the 70s because my grandmother lived there. It's the Interstate 64/65 interchange downtown that made the cut at number 24, after research revealed that there have been 42 fatal accidents connected to this interchange over the last decade. The Interstate 5/California 4 interchange tops the list due to increased truck traffic.