Additional predictions from databases indicate “that glyphosate’s co-toxicity primarily involves kidney injury. As a note, nitrogen metabolism is the pathway with the highest enrichment [higher statistical significance] in both glyphosate-induced kidney injury and kidney cancer, which offers insight into less-explored mechanisms of glyphosate toxicity. Multigenerational effects from glyphosate exposure are also documented, with research associating cancer development with DNA alterations through oxidative stress mechanisms. (See Weed Killer Glyphosate Linked to Multi-Generational Adverse Health Effects and EPA Overlooks Glyphosate and Roundup Ingredients’ Cancer, DNA Damage, and Multigenerational Effects for more information.) (2025) Network toxicology reveals glyphosate mechanisms in kidney injury and cancer, Scientific Reports.