The test assesses changes in a woman’s serum CA125, which could indicate the cancer was present. Heightened riskWomen with the BRCA genes 1 and 2 are at a heightened risk of breast and ovarian cancer. With breast cancer, women can have mammograms to screen for the disease. There is nothing similar for ovarian cancer. For these women, it has the added advantage of catching the cancer early, giving them a greater chance of survival.