A new artificial intelligence (AI) tool can forecast a person’s risk of developing more than 1,000 diseases, in some cases providing a prediction decades in advance. The model, called Delphi-2M, uses health records and lifestyle factors to estimate the likelihood that a person will develop diseases such as cancer, skin diseases and immune conditions up to 20 years ahead of time. The tool’s ability to model multiple diseases in one go is “astonishing,” says Stefan Feuerriegel, a computer scientist at the Ludwig Maximilian University of Munich in Germany, who has developed AI models for medical applications. Oracle of healthResearchers have already developed AI-based tools to predict a person’s risk of developing certain conditions, including some cancers and cardiovascular disease. The authors designed their modified LLM to forecast a person’s likelihood of developing 1,258 diseases on the basis of their past medical history.