The study followed a cohort of patients with an early-stage fatty liver disease, which is linked to changes in brain metabolism that can contribute to cognitive symptoms. The study participants adopted a low-calorie or low-carbohydrate diet for just two weeks and then were screened to see if their brain metabolism markers had improved. These symptoms can be caused by changes in brain metabolism linked to higher-than-normal levels of neurometabolites such as cerebral glutamate and myo-inositol. In the study, participants with MASLD underwent a health screening and brain and liver MRI imaging before being randomly assigned to follow either a low-calorie or a low-carbohydrate diet. “Even short-term, achievable dietary changes may reduce brain processes that contribute to cognitive decline.