Plant-Based Diets and Gout PreventionPlant-based dietary patterns have long been linked to reduced risk of gout, but the specific nutrients responsible for this effect remain unclear. This study sought to clarify whether dietary lignans and whole grain foods are independently protective against gout incidence. Using Cox regression models, investigators evaluated associations between lignan intake, whole grain consumption, and gout risk, adjusting for lifestyle and clinical factors. Key Findings Support Lignans’ Protective RoleHigher intakes of the lignans matairesinol and secoisolariciresinol were linked to a 22% reduction in gout risk when comparing highest to lowest quintiles (HR: 0.78; 95% CI: 0.69–0.90 and HR; 0.78; 95% CI: 0.68–0.89, respectively). ConclusionThese findings strengthen evidence supporting plant-based dietary strategies for gout prevention, highlighting lignans and specific whole grains as protective components.