I-75 North has partially reopened after the interstate was closed at U.S. 50 West/River Road/6th Street, according to the Ohio Department of Transportation. The road remains restricted with the three left lanes blocked beyond the 9th Street on-ramp. One lane is open after a crash shut down I-75 North in downtown Cincinnati on Tuesday, Sept. 23, 2025. Traffic is backed up on northbound lanes of the Brent Spence Bridge at 6:45 a.m. Tuesday, Sept. 12, 2025. This article originally appeared on Cincinnati Enquirer: I-75 North restricted in downtown Cincinnati.