With the participation of the United Arab Emirates, the International Security Alliance (ISA) successfully carried out a joint anti-drug operation targeting transnational criminal groups involved in drug smuggling valued at $2.9 billion. The operation was carried out in cooperation between 25 countries around the world and several international police organizations. The participating countries from the American Police Organisation (Ameripol) were: Colombia, Argentina, Bolivia, Brazil, Chile, Ecuador, Paraguay, El Salvador, Guatemala, Panama, Venezuela, and Peru. From the European Union Organization for Law Enforcement Cooperation (Europol), there was Croatia and Belgium. The Alliance focuses on issues of global significance, foremost among which is combating transnational organized crime, adopting an approach that combines high-level strategic cooperation with operational field participation, ensuring the best results in combating criminal offenses.