“I would say as a scientist, I would love more data.” Still, she says, if you want to try creatine supplements, go for it. The nuanceIf you are taking creatine supplements to boost your performance at the gym or in the sports field, just know the boost might be small. If you want to try itThere are two strategies for getting started on creatine supplements for muscle-building benefits. Transcript: STEVE INSKEEP, HOST: Creatine supplements aren’t just for gym bros, apparently. GODOY: Generally, experts recommend taking three to five grams a day to see the muscle-building benefits of creatine supplements.