(3,4) These findings underscore the need for individualized primary prevention strategies, such as illustrated in the case scenario. (9)Aspirin in Primary Prevention- Rationale & Guideline Recommendations: Aspirin reduces primary cardiovascular events through irreversible COX-1 inhibition in platelets, decreasing thromboxane A2 production, and reducing platelet aggregation. “Hypertension as a risk factor for atherosclerosis: Cardiovascular risk assessment.” Frontiers in cardiovascular medicine vol. “Cardiovascular Disease Risk in South Asians in the Baylor Scott and White Health DILWALE Registry.” JACC. “Aspirin in Primary Prevention: Looking for Those Who Enjoy It.” Journal of clinical medicine vol.