Geographically, the mental health burden reflects stark disparities. The chronicity and relapse potential of many mental disorders necessitate sustained investment in early detection, continuous care models, and integration of mental health services into primary care settings. While this landmark analysis provides vital clarity on the global youth mental health landscape, it also highlights several knowledge gaps and technical challenges. Subject of Research: Global burden of mental disorders, substance use disorders, and self-harm among youthsArticle Title: The burden of mental disorders, substance use disorders, and self-harm among youths globally: findings from the 2021 Global Burden of Disease studyArticle References:Xu, Jj., Ding, Ly., Sun, Cc. The burden of mental disorders, substance use disorders, and self-harm among youths globally: findings from the 2021 Global Burden of Disease study.