HIV among trans women is at crisis levels. Professor Elma de Vries, a family physician, and secretary of the Professional Association for Transgender Health, says gender-affirming healthcare is highly effective in improving health and wellbeing. Two years ago, the HIV Clinician’s Association facilitated the first gender-affirming healthcare guidelines for South Africa. Gender-affirming carePromoting and supporting gender-affirming healthcare guidelines is a sub-objective of the 2023-2028 National Strategic Plan for HIV, TB and STIs. De Vries says all staff at key-populations-friendly facilities should undergo sensitisation training developed by the national health department.