A new study published in the journal of Fertility and Sterility found that women with polycystic ovary syndrome (PCOS) undergo a significantly higher risk of developing type 2 diabetes mellitus (T2DM), even when body weight is taken into account. Within 3 years, 9.2% of women with PCOS developed T2DM, when compared to 6.0% in the matched non-PCOS group. After 15 years, the cumulative incidence rose to 34.3% among women with PCOS, against 22.6% in non-PCOS controls. This suggests that PCOS itself, beyond weight, plays an independent role in elevating diabetes risk. Polycystic ovary syndrome and elevated body mass index independently increase type 2 diabetes risk with obesity-mediated risk dominating: a real-world data analysis of US patients.