Regenerative medicine has just received a promising innovation: a portable device capable of printing biodegradable implants directly into large bone defects. Degradation analysis revealed that implants containing HA degrade more slowly, maintaining stability for the time needed for natural bone to regenerate. Advertisement - Continue Reading BelowTests with pre-osteoblastic cells and human mesenchymal stem cells confirmed that the scaffolds were non-toxic and promoted cell proliferation. Histological analysis after 12 weeks of implantation in rabbits, showing the formation of new bone tissue around the biodegradable scaffold. In situ printing of biodegradable implant for healing critical-sized bone defect.