A groundbreaking perspective has now emerged, focusing on a critical yet often overlooked nexus—the Hg-microbe-GHG axis—and its implications for global mercury mitigation and climate action. This precision will inform policy decisions that harmonize mercury reductions with climate mitigation efforts, rather than pursue these goals in silos. By proactively aligning mercury mitigation with climate action, we can avoid counterproductive responses and leverage co-benefits. Article Title: Aligning global mercury mitigation with climate action. Aligning global mercury mitigation with climate action.