A heart attack happens when arteries become clogged, cutting off blood flow and oxygen to the heart. Normally, when our body gets hurt or infected, the brain quickly sends out signals to activate the immune system. In the past, heart doctors, brain scientists, and immune system experts often worked in separate areas. Instead of only focusing on the heart, future treatments could try to calm down the immune system’s response after a heart attack. Instead of focusing only on opening up arteries and fixing the heart, doctors might also try to manage how the brain and immune system respond.