So, it's possible the effects aren't identical to those of traditional weight loss. Translation: It may not be the weight loss alone that's to blame for your sagging. The product is made to address what Ronert calls the 4 D’s of GLP-1 skin: deflation, density loss, deep wrinkles, and dehydration. Right now, GLP-1 skincare feels inevitable, but some experts caution it’s still ahead of the definitive science. To get a chemist’s perspective, Ursula Diaz, co-founder of , reviewed the ingredient lists for the GLP-1- products.