The early betting line for Clemson’s 2026 season opener has been released. Clemson and LSU will kick off their respective 2026 seasons on Sept. 5, when the two teams face off at Tiger Stadium in Baton Rouge, La. LSU leads the all-time series against Clemson 4-1, with Clemson’s lone win being a dramatic 25-24 victory in the 2012 Peach Bowl. “I know Lane professionally,” Clemson head coach Dabo Swinney said in December. So, obviously he’s a great coach, and that’s a great program.