A recent study published in JAMA Dermatology has demonstrated that PROMIS measures are valid tools for evaluating the physical, emotional, and social effects of chronic skin diseases. Measures assessing physical and social impact were responsive to treatment-related improvements, supporting their use in monitoring patient outcomes. A total of 549 adult patients with chronic skin diseases were considered for the study. Items assessing social satisfaction (SRM, −0.20) and isolation (SRM, 0.27) were as responsive as the Skindex-29 functioning domain (SRM, 0.25). Measurement Properties of PROMIS Measures Relevant to Chronic Skin Diseases.