Type 1 diabetes (T1D) is an autoimmune disorder characterized by the specific destruction of insulin-producing pancreatic β-cells. This review posits that regenerative medicine, particularly strategies centered on stem cells and pancreatic progenitor cells, holds the key to a lasting cure. The Search for Elusive Pancreatic Stem CellsA central quest in the field is the identification of endogenous pancreatic stem or progenitor cells in adults. Concurrently, the derivation of β-like cells from pluripotent stem cells (e.g., embryonic or induced pluripotent stem cells) has progressed to clinical trials (e.g., ViaCyte, Vertex Pharmaceuticals), showing restored insulin production in patients. Reference:Chakrabarti SK, Chattopadhyay D. The Future of Type 1 Diabetes: Can Stem Cells Provide a Cure?Explor Res Hypothesis Med.