If you weren’t born with them naturally, you would have to turn to filler to get the juicy, plump lips of your dreams. “It is positioned in cosmetics as an agent that enhances skin volume and contour by affecting lipid metabolism in subcutaneous fat cells,” Bonjout says. “[It] is basically a plumping ingredient,” adds cosmetic chemist and founder of KKT Labs Krupa Koestline. Hadley Kina g, MD, a New York City-based board-certified dermatologist, says that volufiline works by stimulating fat cells to store lipids in hypodermis, a.k.a. Bonjout points out a small study done by Sederma that showed a 2.2% increase in breast volume after 56 days of applying volufiline topically.