The biggest comeback in Super Bowl history is better known by 28-3NFL: NOV 18 Patriots at Falcons | Icon Sportswire/GettyImagesThe Falcons sure seemed poised to win their first-ever Super Bowl when Robert Alford's pick-six put them up 21-0 over the New England Patriots in Super Bowl LI. The five biggest comebacks in Super Bowl historyA look at the biggest comebacks in Super Bowl history shows just how absurd the Patriots' win was. Their most impressive comeback of the three also happened to be their first Super Bowl win of the Patrick Mahomes era. Super Bowl LVIII (Chiefs vs. 49ers)49ers fans are likely just as frustrated as Falcons fans, knowing they've blown two of the largest leads in Super Bowl history. Remarkably, if they were able to recover an onside kick, they'd have a golden opportunity to win the Super Bowl.