articleThe Brief The world's least affordable city to buy a home is in the Bay Area. A new analysis of home price affordably found that the city with the least affordable housing market in the world was in the Bay Area. Other Bay Area citiesSan Francisco:Further down the rankings, San Francisco came in as the world’s tenth least affordable city for homebuying. No other U.S. city made the list of the world’s top 10 most affordable cities to buy a home. When the list was narrowed down to the top 10 most affordable cities in North America, California failed to show up.