The approaches are generalizable, offering a blueprint for engineering microbes to make a wide range of bio-based products. One combines artificial intelligence and lab automation to rapidly test and refine the genetic designs of biofuel-producing microbes. By contrast, the Berkeley Lab researchers built an automated pipeline that uses robotics to create and test hundreds of genetic designs in parallel. ###Lawrence Berkeley National Laboratory (Berkeley Lab) is committed to groundbreaking research focused on discovery science and solutions for abundant and reliable energy supplies. Berkeley Lab is a multiprogram national laboratory managed by the University of California for the U.S. Department of Energy’s Office of Science.