UKHSA says 'be aware' after 5,424 cases of 'deadliest' infection in EnglandThe symptoms can be mistaken for something much less seriousView Image It is a bacterial infection that most frequently affects the lungsThe UK Health Security Agency (UKHSA) has revealed that there were 5,424 cases of tuberculosis in England in 2025, roughly similar to the number of 2024 - 5,487. ‌81.6% of all TB notifications in 2025 were in people born outside the UK, consistent with previous years. TB notifications were stable in five of the nine UKHSA regions. ‌Dr Esther Robinson, Head of the TB Unit at UKHSA, said: "TB remains a serious public health issue in England. To detect people with latent TB infection, a testing and treatment programme is in place in higher incidence areas of England for new arrivals from higher incidence countries.