Charity Pierce, who appeared on the TLC show My 600-lb Life, has died at age 50 after reportedly suffering from various health ailments. Pierce, who was once known as the 'world's fattest woman' after weighing in at 778 pounds, chronicled her efforts to lose weight on the TLC series, where she would ultimately drop 440 pounds. The source said various medical conditions had resulted in Pierce being placed in hospice care for the past month or two. Pierce was first featured on My 600-Lb Life in 2015 followed by appearances in the follow-up show, My 600-Lb Life: Where Are They Now? Pierce had undergone a massive transformation with her results visible on the follow-up show, TLC's My 600lb Life; Where Are They Now?