They set out to evaluate the effects of the test cream, dubbed “Gold Hakuyo all-in-one cream”, on 14 healthy female subjects aged 31 to 59. Expert inspectors, who were kept blinded to which side of the face received the treatment, evaluated the wrinkle grade from photographs taken before and after the four-week period. Their assessment showed a statistically significant difference in wrinkle grade reduction on the test side. This led the team to conclude that the product proved “effective in reducing wrinkles in relatively elderly subjects with a high wrinkle grade”. As the test cream was designed to be an all-in-one product, the researchers concluded that there was “no need to use multiple cosmetic products other than the test cream”.