The rapid integration of precision medicine into the treatment of endometrial cancer has transformed clinical workflows, shifting the focus from broad histopathologic categories to specific molecular drivers. In a Community Case Forum event, John K. Chan, MD, director of Gynecologic Oncology and a specialist in the surgical and medical treatment of ovarian and other complex pelvic cancers at the UCSF Helen Diller Family Comprehensive Cancer Center, moderated a discussion with oncologists in Denver, Colorado about molecular testing and treatment decisions in patients with endometrial cancer. CASE SUMMARYA 71-year-old postmenopausal woman presented with abnormal uterine bleeding, increasing urinary frequency, nausea, and abdominal cramping for approximately 6 months. But I think it’s tough to know, should I be doing more than just asking my nurse to send Caris NGS? You’re almost relying on them, especially when uterine cancer is not the predominant disease that you deal with, right?