Biotechnology pioneer Genentech broke ground Monday on a $700 million manufacturing facility in Holly Springs, marking the company's first production site on the East Coast and a significant expansion of North Carolina's life sciences sector. Josh Stein joined federal and local officials at the groundbreaking ceremony, highlighting North Carolina's growing prominence in biotechnology manufacturing. Company rendering of future finished site in Holly Springs. U.S. Representative Deborah Ross, whose district includes Holly Springs, called the investment "a milestone for our community and for North Carolina's growing role in the biotech economy." Holly Springs Mayor Sean Mayefskie emphasized the facility's expected impact on local businesses, calling it "a defining step forward" that will "strengthen Holly Springs' role as a cornerstone in North Carolina's life sciences manufacturing ecosystem."