Cancer cells are characterized by their increased glucose uptake, a phenomenon known as the Warburg effect. Existing methods for metabolic analysis often struggle to fully elucidate these cancer-specific pathways due to the inherent complexities of cellular metabolism. Understanding the unique metabolic characteristics of cancer cells is crucial for developing effective cancer treatments. We believe this will pave the way for the development of innovative therapeutic strategies targeting cancer-specific metabolic pathways." ###The article, “Metabolic flux and flux balance analyses indicate the relevance of metabolic thermogenesis and aerobic glycolysis in cancer cells,” was published in Metabolic Engineering at DOI: https://doi.org/10.1016/j.ymben.2025.08.002