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EN
Porous polymer coatings with rifampicin prevent catheter infections
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European Coatings
A research team from China has developed an innovative coating that could substantially lower the risk of catheter-associated urinary tract infections.
The coatings are based on polylactic acid (PLA) and were engineered using techniques such as breath fig (BF), inverse emulsion (Ie), and vapour-induced phase separation (VIPS) to create a highly porous structure.
Drug release tests revealed an initial burst within 24 hours, followed by a sustained release lasting up to 28 days.
Highly porous Ie-BF coatings achieved the highest cumulative release rate of 87.45 %.
Source: Lin, P. et al., Fabrication of highly porous polymeric coatings loaded with rifampicin for preventing catheter-associated urinary tract infections.
['rifampicin'
'infections'
'tests'
'coatings'
'research'
'release'
'prevent'
'highly'
'tract'
'polymer'
'catheter'
'porous'
'urinary']