To selectively delete files in the Downloads folder, open the folder in File Explorer. Is it possible to set up my PC to automatically clean the Downloads folder periodically? You can automatically clean your PC’s Downloads folder by utilizing Windows’ “Storage Sense” feature, found in the System settings under “Storage”. On Android devices, this might be called “Files,” “My Files,” “File Manager,” or something similar. Clearing your browser cache does not delete files you’ve downloaded and saved to your computer or device.