Brief SynthesisLocated in the Mosquitia region of Northeastern Honduras, Río Plátano Biosphere Reserve is the largest protected area in the country with 350,000 hectares. Criterion (vii): The natural beauty of Río Plátano Biosphere Reserve is a function of the variety of the terrain and landscape types and features. In terms of nature conservation, Río Plátano Biosphere Reserve was originally designated in 1980 by Decree and substantially extended in 1997 by a further Decree. Despite the strong legal protection, Río Plátano Biosphere Reserve has long been suffering from human pressure threatening its integrity. Future management of Río Plátano Biosphere Reserve should also promote an enhanced understanding and protection of the many archaeological sites hidden in the dense forests.